半胱氨酸
荧光
化学
纳米材料
新陈代谢
生物物理学
糖酵解
碳纤维
生物化学
纳米技术
材料科学
生物
复合数
物理
复合材料
酶
量子力学
作者
Feng Li,Yiye Li,Xiao Yang,Xue Han,Yang Jiao,Taotao Wei,Dayong Yang,Huaping Xu,Guangjun Nie
标识
DOI:10.1002/anie.201712453
摘要
Abstract Cysteine‐based chiral optically active carbon dots (CDs) and their effects on cellular energy metabolism, which is vital for essential cellular functions, have been barely reported. A green and effective synthesis strategy for chiral N‐S‐doped CDs (fluorescence quantum yield ca. 41.26 %) based on hydrothermal treatment of l ‐ or d ‐cysteine at as low as 60 °C has been developed. This suggested that cysteine was instable in aqueous solutions and acts as a warning for high‐temperature synthesis of nanomaterials using cysteine as stabilizer. Human bladder cancer T24 cells treated with l ‐CDs showed up‐regulated glycolysis, while d ‐CDs had no similar effects. In contrast, no disturbance to the basal mitochondrial aerobic respiration of T24 cells was caused by either chiral CD.
科研通智能强力驱动
Strongly Powered by AbleSci AI