白杨素
生物利用度
蜂胶
药理学
化学
黄酮类
作用机理
体内
抗氧化剂
生物化学
类黄酮
体外
生物
生物技术
食品科学
色谱法
作者
Renuka Mani,Natesan Vijayakumar
出处
期刊:Phytochemistry
[Elsevier]
日期:2017-11-21
卷期号:145: 187-196
被引量:330
标识
DOI:10.1016/j.phytochem.2017.09.016
摘要
In recent years, public and scientific interest in plant flavonoids has tremendously increased because of their postulated health benefits. This review was mainly focuses on the flavone chrysin (5,7-dihydroxyflavone), which occurs naturally in many plants, honey, and propolis. A number of in vitro and in vivo studies have revealed the therapeutic effects of chrysin against various diseases. In general, chrysin exhibits many biological activities and pharmacological effects, including antioxidant, anti-inflammatory, anticancer, and antiviral activities. Moreover, many studies have reported on the bioavailability of chrysin. Because of its compromised bioavailability and enhanced protein stability, chrysin solid lipid nanoparticle (SLN) synthesis avoids proteolytic degradation and sustained release of drug delivery. To clarify the mechanism of action of chrysin, researchers have investigated the structural binding relationship of chrysin through the docking computation method.
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