Topographic analysis of esophageal double-peaked waves

蠕动 食管 解剖 医学 压力波 收缩(语法) 地质学 内科学 物理 机械
作者
Ray E. Clouse,Annamaria Staiano,Aydamir Alrakawi
出处
期刊:Gastroenterology [Elsevier BV]
卷期号:118 (3): 469-476 被引量:55
标识
DOI:10.1016/s0016-5085(00)70252-6
摘要

Esophageal double-peaked waves occur with increased frequency in patients with functional esophageal symptoms. This study was undertaken to further understand the mechanisms responsible for their production.Topographic methods that consider temporal and spatial relationships of pressure data were used to examine 74 double-peaked waves detected in 18 subjects referred for manometric evaluation of unexplained symptoms. The studies were performed with a computerized data acquisition and analysis system designed for topographic plotting.The second peak appeared to represent muscle contraction that merged with an unusually strong pressure site in the third topographic segment and covered 6.3 +/- 1.6 cm (33.5% +/- 8.5% esophageal length) proximal to this site. In 50 swallows (67.6%), the peak itself progressed in a retrograde direction at 13.2 +/- 10.8 cm/s, suggesting cephalad extension of a strong distal motor event. Analysis of wave onsets and movement of the peristaltic trailing edge detected retrograde propagation in up to 33.8% of waves, antegrade propagation in 2.7%, and simultaneous contraction in the remainder.In symptomatic patients, the second peak in a double-peaked wave is typically a short, simultaneous, or retrograde pressure event in the region of and merging with the third topographic segment in the distal esophageal body. Topographic methods help explain the common association of these waveforms with other features of exaggerated contraction in the distal esophagus and suggest their relationship to inadequate inhibitory nerve function.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刻苦熠彤应助飞云采纳,获得10
刚刚
刚刚
zhang完成签到 ,获得积分10
1秒前
李爱国应助无名采纳,获得10
1秒前
nannan发布了新的文献求助10
1秒前
鲁彦华完成签到,获得积分20
2秒前
2秒前
Jason发布了新的文献求助10
4秒前
4秒前
Loong完成签到,获得积分10
5秒前
科研通AI2S应助sigla采纳,获得10
5秒前
5秒前
5秒前
卷儿完成签到,获得积分10
6秒前
6秒前
大钱完成签到,获得积分10
7秒前
7秒前
卞斌锋完成签到 ,获得积分20
7秒前
7秒前
7秒前
7秒前
7秒前
我是老大应助淡淡的新之采纳,获得10
8秒前
慕青应助CX采纳,获得10
8秒前
8秒前
8秒前
9秒前
9秒前
hanchangcun发布了新的文献求助10
10秒前
Xianhe完成签到,获得积分10
10秒前
summer发布了新的文献求助10
10秒前
可可发布了新的文献求助10
11秒前
11秒前
今后应助kiwiii采纳,获得10
11秒前
假唱卡带完成签到,获得积分10
11秒前
李青秀发布了新的文献求助20
11秒前
garey发布了新的文献求助10
12秒前
12秒前
Leeyee发布了新的文献求助10
12秒前
段红琼发布了新的文献求助30
12秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Cognitive Neuroscience: The Biology of the Mind 1000
Technical Brochure TB 814: LPIT applications in HV gas insulated switchgear 1000
Toward a Combinatorial Approach for the Prediction of IgG Half-Life and Clearance 500
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Picture Books with Same-sex Parented Families: Unintentional Censorship 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3970120
求助须知:如何正确求助?哪些是违规求助? 3514810
关于积分的说明 11176124
捐赠科研通 3250136
什么是DOI,文献DOI怎么找? 1795198
邀请新用户注册赠送积分活动 875647
科研通“疑难数据库(出版商)”最低求助积分说明 804964