Expedient stereospecific Co-catalyzed tandem C–N and C–O bond formation of N-methylanilines with styrene oxides

Cobalt(ii)-catalyzed stereospecific coupling of N-methylanilines with styrene oxides is developed via tandem C-N and C-O bond formation using tert-butyl hydroperoxide (TBHP) as an oxidant. Optically active epoxide can be reacted with high optical purity.