Environmental concentrations of azinphos-methyl cause different toxic effects without affecting the main target (cholinesterases) in the freshwater gastropod Biomphalaria straminea

超氧化物歧化酶 生物 过氧化氢酶 有机磷 杀虫剂 毒理 后代 毒性 羧酸酯酶 谷胱甘肽 生态毒理学 淡水蜗牛 孵化 抗氧化剂 生态学 生物化学 化学 蜗牛 有机化学 遗传学 怀孕
作者
Paula Fanny Cossi,Lucila Thomsett Herbert,María Soledad Yusseppone,Analía F. Pérez,Gisela Kristoff
出处
期刊:Ecotoxicology and Environmental Safety [Elsevier]
卷期号:162: 287-295 被引量:22
标识
DOI:10.1016/j.ecoenv.2018.06.091
摘要

Organophosphate insecticides (OPs) are commonly used in Argentina and around the world for pest control in food crops. They exert their toxicity through the inhibition of the enzyme acetylcholinesterase. In the present study, we aimed to evaluate biochemical and reproductive effects in Biomphalaria straminea, a freshwater gastropod naturally distributed in Argentina, of subchronic exposures to environmental azinphos-methyl concentrations (20 and 200 µg L-1). For biochemical parameters, adult organisms were exposed for 14 days and the activity of cholinesterases (ChEs), carboxylesterases (CEs), glutathione S-transferase (GST), catalase (CAT), superoxide dismutase (SOD), the production of reactive oxygen species (ROS), the total antioxidant capacity (TAC), glycogen and proteins were determined. For reproductive parameters, the egg masses of B. straminea were exposed to azinphos-methyl for one month, and the hatching time and success as well as the offspring survival were registered. We found different toxic effects elicited by the insecticide on the studied biomarkers. CEs activity was significantly inhibited while CAT and GST activities, ROS production and TAC were significantly increased, with respect to the solvent control group. ChE and SOD activities and protein and glycogen contents were not altered by azinphos-methyl. The hatching time and success were not statistically different from control. Nevertheless, the offspring survival was severely affected by the insecticide. Our results show that the primary target of the insecticide (ChE) was not inhibited but CEs, GST, CAT, ROS, TAC and offspring survival were sensitive biomarkers and valuable endpoints for subchronic toxicity assessments in this species.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
水三寿完成签到,获得积分20
1秒前
1秒前
xuanyu应助神勇的香魔采纳,获得10
2秒前
吉祥财子完成签到,获得积分10
2秒前
3秒前
nwds完成签到,获得积分10
3秒前
林也行完成签到,获得积分10
4秒前
4秒前
xuxian完成签到 ,获得积分10
4秒前
沉默的谷秋完成签到,获得积分10
5秒前
新明完成签到,获得积分10
5秒前
7秒前
8秒前
9秒前
caikeke发布了新的文献求助10
9秒前
Ting发布了新的文献求助10
9秒前
10秒前
上官若男应助hxd采纳,获得10
10秒前
10秒前
AppleDog发布了新的文献求助10
12秒前
13秒前
Yjh发布了新的文献求助10
13秒前
谦让夜香完成签到,获得积分10
15秒前
Cat应助胡豆豆采纳,获得30
16秒前
16秒前
19秒前
耍酷千山发布了新的文献求助10
19秒前
一碗鱼发布了新的文献求助10
20秒前
min17完成签到,获得积分10
20秒前
AppleDog完成签到,获得积分10
21秒前
goodesBright应助wwwchhh采纳,获得10
21秒前
夏果果发布了新的文献求助10
21秒前
追寻紫安应助狂野的念波采纳,获得10
21秒前
22秒前
22秒前
何哈哈完成签到,获得积分10
23秒前
Yvonne发布了新的文献求助10
24秒前
25秒前
平淡问雁发布了新的文献求助10
26秒前
26秒前
高分求助中
Sustainability in Tides Chemistry 1500
TM 5-855-1(Fundamentals of protective design for conventional weapons) 1000
CLSI EP47 Evaluation of Reagent Carryover Effects on Test Results, 1st Edition 800
Threaded Harmony: A Sustainable Approach to Fashion 799
Livre et militantisme : La Cité éditeur 1958-1967 500
Retention of title in secured transactions law from a creditor's perspective: A comparative analysis of selected (non-)functional approaches 500
"Sixth plenary session of the Eighth Central Committee of the Communist Party of China" 400
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3055485
求助须知:如何正确求助?哪些是违规求助? 2712292
关于积分的说明 7430453
捐赠科研通 2357116
什么是DOI,文献DOI怎么找? 1248604
科研通“疑难数据库(出版商)”最低求助积分说明 606750
版权声明 596093