Synthesis of tetrasubstituted thiophenes via a [3+2] cascade cyclization reaction of pyridinium 1,4-zwitterionic thiolates and activated allenes

A [3+2] cascade cyclization reaction of pyridinium 1,4-zwitterionic thiolates and activated allenes has been developed, which allows facile access to a library of tetrasubstituted thiophenes with great variety under thermal conditions.