Silver nanoparticles incorporated polyaniline on TiO2 nanotube arrays: A nanocomposite platform to enhance the biocompatibility and antibiofilm

The premature failure of titanium orthopaedic implant occurs mainly due to infections and non-reunion of fractures. Encouragingly, the controlling of infections and fracture reunion was effective with metal nanoparticles and conducting polymers. In this present work, the nanocomposite of silver nanoparticles incorporated polyaniline (PANI) on TiO2 nanotube arrays (TNTA) was fabricated by electropolymerization. The nanocomposite had effectively declined the rate of biofilm formation and enhanced cellular responses. Moreover, the corrosion rate was regressed that undermines the release of titanium wear-out particles. Collectively, the work illustrates the significant usage of multifunctional nanocomposite for achieving the synergetic effect on antibiofilm, antibacterial and better osseointegration.