多糖
高脂血症
四氧嘧啶
化学
糖原
血脂
脂质代谢
根茎
内分泌学
糖尿病
食品科学
内科学
胆固醇
生物化学
传统医学
医学
作者
Yu Lian,Jie Zhang,Jun Jiao,Jin Su,Weitong Sun,Yu Guo,Ma ShuXia,Tao Zhang,Dexin Meng
出处
期刊:PubMed
日期:2020-01-01
卷期号:33 (1(Special)): 481-487
被引量:10
摘要
Chinese yam is the dry rhizome of dioscoreaceae plant. Polysaccharide in yam is one of significant functional components, its pharmacological effects include glucose-lowering, lipid-lowering, anti-tumor, anti-oxidation and enhancing the immune. The effects of nano yam polysaccharide on the metabolism of blood glucose and blood lipid in model rats were systematically investigated in this study. The results showed that the diabetic rat model can been successfully induced by the peritoneal injection of 200mg/kg alloxan. The rats were fed with the high-fat diet for 30d, which could induce a model of hyperlipidemia rat successfully. After the model rats were fed with nano yam polysaccharide of 50mg/ml and 100mg/ml per day for 12d and 30d, respectively. For each nano yam polysaccharide group, the blood glucose level was significantly reduced, the glucose tolerance, glycogen and the content of C-peptide were improved in alloxan rats. Moreover, the symptom of one little and three more in diabetic rats was ameliorated and the contents of TC, TG and LDL-C in the serum for the high fat rats were significantly decreased.
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