Lignans from Patrinia scabra

Objective To study the lignans in Patrinia scabra. Methods The constituents were separated and purified by column chromatographies with silica gel, RP-silica gel, and Sephadex LH-20. Their structures were elucidated on the basis of spectral data (IR, MS, 1H-NMR , 13 C-NMR , DEPT, HMQC and HMBC). Results There were four lignans obtained from P. scabra with the structures identified as pinoresinol-4, 4′-di-O-β-D-glucopyranoside (Ⅰ), and matairesinol-4, 4′-di-O-β-D-glucopyranoside (Ⅱ), lariciresinol-4′-O-β-D-glucopyranoside (Ⅲ), and lariciresinol-4-O-β-D-glucopyranoside (Ⅳ). Conclusion All the four compounds are found in P. scabra for the first time. The NMR data of compound Ⅱ are given first.