In Vitro and In Vivo Removal of Anti‐A Erythrocyte Antibody by Adsorption to a Synthetic Immunoadsorbent

A solid‐phase immunoadsorbent column using blood group A trisaccharide was tested in vitro and in vivo in dogs. This column was demonstrated to specifically remove anti‐A antibody from human plasma in vitro and in vivo dogs specifically immunized with synthetic human blood group A trisaccharide. These studies indicate that this technique will be useful in removing anti‐A and B antibody in marrow transplant recipients of incompatible marrow.