Self-assembly of GO-MXene hybrid composites by polyelectrolyte: As an efficient electrocatalyst for selective electrochemical detection of the antibiotic furazolidone

The construction of an efficient electrochemical sensor for the detection of furazolidone antibiotics is important for drug analysis and environmental monitoring. In this work, we present a study reporting the detection of furazolidone by polyelectrolyte poly(diallyldimethyl-ammonium chloride) (PDDA) assembled GO and MXene composite (GM-P) modified screen printed electrodes. The GM-P composites were prepared utilizing an efficient and rapid ultrasound-assisted self-assembly strategy. The robust and stable GM-P consisting of two-dimensional MXene and GO flakes can effectively inhibit the aggregation of the two and increase the surface area, thus providing abundant active sites to promote the penetration of electrolytes, attachment of furazolidone (FZD), and thus improve the electrochemical detection performance. Based on this, the electrochemical sensor possesses favorable electrochemical sensing performance for FZD, including wide linear detection range, low detection limit and high sensitivity. In addition, the sensor was very successful in detecting FZDs in tap and river water, highly substantiating the potential of its application in real-world samples. Thus, this work not only provides a high-performance electrode for electrochemical sensing, but also a simple and practical strategy for constructing MXene or GO composites, which have great potential for supercapacitors or batteries.