化学
反应性(心理学)
光化学
电化学
氧化还原
硫醚
电子转移
催化作用
氧气
锰
分子
基质(水族馆)
无机化学
组合化学
有机化学
电极
物理化学
医学
替代医学
病理
海洋学
地质学
作者
Md Asmaul Hoque,James B. Gerken,Shannon S. Stahl
出处
期刊:Science
[American Association for the Advancement of Science (AAAS)]
日期:2024-01-11
卷期号:383 (6679): 173-178
被引量:23
标识
DOI:10.1126/science.adk5097
摘要
The reactivity of molecular oxygen is crucial to clean energy technologies and green chemical synthesis, but kinetic barriers complicate both applications. In synthesis, dioxygen should be able to undergo oxygen atom transfer to two organic molecules with perfect atom economy, but such reactivity is rare. Monooxygenase enzymes commonly reductively activate dioxygen by sacrificing one of the oxygen atoms to generate a more reactive oxidant. Here, we used a manganese-tetraphenylporphyrin catalyst to pair electrochemical oxygen reduction and water oxidation, generating a reactive manganese-oxo at both electrodes. This process supports dioxygen atom transfer to two thioether substrate molecules, generating two equivalents of sulfoxide with a single equivalent of dioxygen. This net dioxygenase reactivity consumes no electrons but uses electrochemical energy to overcome kinetic barriers.
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