Protein-energy wasting (PEW) has high incidence in hemodialysis patients and refers to a state of decreased protein and energy substance. With the extensive development of hemodialysis in patients with end-stage kidney disease, most patients with maintenance hemodialysis have the problem of PEW, which is one of the common complications of maintenance hemodialysis patients, resulting in decreased quality of life and increased mortality. This article searches and analyzes the literature in recent years to summarize the current influencing factors and common interventions of PEW in maintenance hemodialysis patients, which will provide reference for subsequent nutritional management of maintenance hemodialysis patients.