小RNA
鉴定(生物学)
计算生物学
生物
甲氨蝶呤
遗传学
基因
免疫学
植物
作者
Mengmeng Zhang,Zhenmin Niu,Qiong Huang,Ling Han,Juan Du,Jun Liang,Yanwen Cheng,Ruoshui Cao,Nikhil Yawalkar,Zhenghua Zhang,Kexiang Yan
标识
DOI:10.1016/j.intimp.2024.112280
摘要
Methotrexate (MTX) is an economic and effective medicine treatment for psoriasis. Extracellular vesicle (EV) miRNA biomarkers related to its efficiency have been identified in various diseases. Whether certain miRNA profiles are associated with psoriasis treatment is unknown. In order to determine specific miRNA biomarkers for MTX effectiveness prediction and the severity of psoriasis, our study looked at the variations in circulating EV miRNA profiles before and after MTX therapy.
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