[Application of Tiaojing Cuyun acupuncture in treatment of diseases with ovarian function decline].

Taking regulating the thoroughfare vessel and the conception vessel, tonifying liver and kidney, calming mind as the treatment principle, Tiaojing Cuyun acupuncture (acupuncture for regulating menstruation and promoting pregnancy) is commonly used in clinical treatment of diseases with ovarian function decline, and recommends full cycle acupuncture treatment. Clinical research shows that Tiaojing Cuyun acupuncture can improve menstruation and ovulation, increase the reserve function and response of ovary as well as endometrial receptivity, so as to improve the pregnancy outcome. It can also improve the related symptoms caused by negative emotions and low estrogen, and comprehensively enhance the health related quality of life in patients. The mechanism of Tiaojing Cuyun acupuncture mainly involves 2 aspects, i.e. overall regulation on hypothalamus-pituitary-ovary (HPO) axis and the local regulation on FSH/cAMP signal transduction in ovarian granulosa cells.调经促孕针法以调冲任、补肝肾、安神志为治疗原则，临床应用于卵巢功能衰退性疾病，提倡全周期针刺治疗。临床研究表明该法可改善月经及排卵情况，提高卵巢储备功能、反应性及子宫内膜容受性，从而影响妊娠结局；改善负性情绪及雌激素低下引起的症状，综合提高患者健康相关生活质量。主要机制涉及下丘脑-垂体-卵巢（HPO）轴整体调节和卵巢颗粒细胞促卵泡激素（FSH）/环磷酸腺苷（cAMP）信号转导局部调节两方面。.