作者
Matteo Lambertini,Eva Blondeaux,Elisa Agostinetto,Anne-Sophie Hamy,Hee Jeong Kim,Antonio Di Meglio,R. Bernstein Molho,Florentine Hilbers,Katarzyna Pogoda,Estela Carrasco,Kevin Punie,Jyoti Bajpai,Michail Ignatiadis,Halle C. F. Moore,Kelly‐Anne Phillips,Angela Toss,Christine Rousset‐Jablonski,Fedro A. Peccatori,Tiphaine Renaud,Alberta Ferrari,Shani Paluch–Shimon,Robert Fruscio,Wanda Cui,Stephanie M. Wong,Claudio Vernieri,Kathryn J. Ruddy,Maria Vittoria Dieci,Alexios Matikas,Mariya Rozenblit,Cynthia Villarreal-Garza,Laura De Marchis,Lucia Del Mastro,Fabio Puglisi,Maria Del Pilar Estevez Diz,Kenny A. Rodriguez‐Wallberg,Bela Mriňáková,Sarah Meister,Luca Livraghi,Florian Clatot,Rinat Yerushalmi,Carmine De Angelis,Rodrigo Sánchez-Bayona,Icro Meattini,Natalia Cichowska-Cwalińska,Martine Berlière,Mahmoud Salama,Ugo De Giorgi,Amir Sonnenblick,Camila Chiodi,Young‐Jin Lee,Camille Maria,Hatem A. Azim,Luca Boni,Ann H. Partridge
摘要
(Abstracted from JAMA 2024;331(1):49–59 Individuals who are diagnosed with breast cancer at a young age are often carriers of a pathogenic variant in the BRCA1 or BRCA2 genes, and many young women in this situation are interested in preserving future fertility, if possible. Reproductive counseling in this situation can be complex due to the risk of passing on the variant, as well as the implications on their own fertility, as the mutation can impact ovarian reserve, fertility potential, and other factors.
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