Brevibacillus sp. and Brevibacillin: Biosynthesis, Classification, Bioactivity, and Potential Applications

The bacterium Brevibacillus laterosporus, which forms spores, is found in various environments, including soil, water, plants, and food. Parasporal crystals of B. laterosporus are well known for their insecticidal properties against a wide range of invertebrate pests. In the chapter, the isolation and identification of various antimicrobials produced by B. laterosporus, such as lacterosporamine (C17H35N7O4), Basiliskamide A and Basiliskamide B, Tostadin, Gramicidin A-C, Gramididin S, Tyrocidine A-C, laterocidin, and Loloatin A-D, and the linear lipopeptides Bogorol AE, Brevibacillin were reviewed. Furthermore, their antimicrobial mechanism, biosynthesis, and potential applications in food and agriculture were introduced.