Personnel management in colleges and universities is an important work, personnel department functions are complicated and important, the use of information technology can improve efficiency and accuracy. Aiming at low level of informatization of personnel office in universities and cumbersome data organization problems, we design and develop a personnel office service platform based on WeChat applet. The service platform and Python The service platform and Python background can interact with each other to realize the management function of personnel office service platform. The test shows that the personnel office service platform based on WeChat applet improves the efficiency of teaching staff and personnel managers. The test shows that the personnel office service platform based on WeChat applet improves the efficiency of teaching staff and personnel management personnel, and achieves the functions required by the design.