免疫疗法
逃避(道德)
临床试验
医学
免疫系统
癌症
抗原
肿瘤相关抗原
癌症免疫疗法
免疫学
癌症研究
肿瘤科
内科学
作者
Ugur Uslu,Carl H. June
出处
期刊:Cancer immunology research
[American Association for Cancer Research]
日期:2023-06-22
卷期号:: OF1-OF1
标识
DOI:10.1158/2326-6066.cir-23-0160
摘要
Abstract In this issue, Tsimberidou and colleagues report the results of a first-in-human clinical trial using a personalized, multi-target, endogenous T-cell therapy in patients with metastatic solid tumors. This, and results of other recently published clinical trials, confirms the rationale of multi-target approaches that can increase tumor responses and counteract tumor heterogeneity and mechanisms of immune evasion. See related article by Tsimberidou et al., p. 925 (4).
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