Dietary Inflammatory Index and all-cause mortality among asthma patients: a population-based cohort study

医学 哮喘 体质指数 危险系数 内科学 比例危险模型 置信区间 糖尿病 队列 人口 环境卫生 内分泌学
作者
Ya-Mei Yuan,Weidong Ye,Xiangming Fang
出处
期刊:Annals of palliative medicine [AME Publishing Company]
卷期号:11 (6): 2061-2070 被引量:6
标识
DOI:10.21037/apm-22-615
摘要

Background: Inflammatory response plays a crucial role in the development and deterioration of asthma.The aim of this study was to assess the association between Dietary Inflammatory Index (DII) score and allcause mortality among patients with asthma in the United States (US). Methods:We included participants aged ≥20 years and excluded those with no data relating to 24-hour dietary recall of dietary intake interview and asthma status.DII score was calculated based 25 food parameters.Multivariate Cox regression analysis was used to analyze the linear association between DII score and all-cause mortality, and a generalized additive model (GAM) with a spline smoothing function was used to analyze the nonlinear dose-response relationship.Results: Among the 20,573 participants, 2,805 (13.63%) participants had a current or past diagnosis of asthma, and 17,768 (86.37%) participants had no history of asthma.DII score was associated with increased all-cause mortality among participants who had previously been diagnosed with asthma [hazard ratio (HR):1.13; 95% confidence interval (CI): 1.04, 1.23; P=0.004] and participants who were currently diagnosed with asthma (HR: 1.13; 95% CI: 1.03, 1.24; P=0.010) after multivariable adjustment for age, sex, race, education, family income, body mass index, physical activity, smoking status, diabetes, hypertension, and coronary heart disease.When DII score was transformed into a categorical variable, participants with a current or past diagnosis of asthma who were in the DII score fifth quintile were associated with increased all-cause mortality when compared with participants in the lowest quintile (HR: 2.34; 95% CI: 1.34, 4.11).The association was stronger in these participants than in participants with no history of asthma (HR: 1.25; 95% CI: 1.04, 1.49).Furthermore, the GAM model showed a linear dose-response relationship, which indicated that increased DII score was associated with increased all-cause mortality among participants with a current or past diagnosis of asthma.Conclusions: Our study is the first to provide evidence that DII score is associated with increased allcause mortality among patients with asthma in the US.Due to potential bias and residual confounding, our findings require further investigation and confirmation in randomized controlled trials.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
曾经幻柏发布了新的文献求助10
1秒前
木木水完成签到,获得积分10
2秒前
面壁思过应助奋斗的萝采纳,获得10
2秒前
呼之欲出发布了新的文献求助10
2秒前
2秒前
Hancock发布了新的文献求助10
2秒前
ahey发布了新的文献求助30
2秒前
3秒前
3秒前
5秒前
007发布了新的文献求助10
5秒前
5秒前
6秒前
6秒前
vlots应助发呆的小号采纳,获得30
7秒前
曲凯完成签到 ,获得积分10
7秒前
8秒前
今后应助zh采纳,获得10
9秒前
魏少爷发布了新的文献求助10
9秒前
orixero应助郭娅楠采纳,获得10
9秒前
易柒完成签到,获得积分10
10秒前
dandan完成签到 ,获得积分10
10秒前
负负发布了新的文献求助10
11秒前
冰释完成签到,获得积分10
11秒前
11秒前
沐夕完成签到,获得积分10
13秒前
SYLH应助康康采纳,获得20
13秒前
曾经幻柏完成签到,获得积分10
13秒前
14秒前
15秒前
dandan关注了科研通微信公众号
17秒前
17秒前
18秒前
19秒前
量子星尘发布了新的文献求助10
20秒前
zh发布了新的文献求助10
20秒前
SJ_Wang完成签到,获得积分10
20秒前
郭娅楠发布了新的文献求助10
20秒前
21秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 700
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3975722
求助须知:如何正确求助?哪些是违规求助? 3520056
关于积分的说明 11200719
捐赠科研通 3256455
什么是DOI,文献DOI怎么找? 1798271
邀请新用户注册赠送积分活动 877490
科研通“疑难数据库(出版商)”最低求助积分说明 806390