药品
药物制剂
药效学
药理学
溶解度
药代动力学
化学
差示扫描量热法
材料科学
色谱法
医学
有机化学
物理
热力学
作者
Abdulrahman A. Al‐Majed,Ahmed H. Bakheit,Ali Al-Muhsin,Hamad M. Alkahtani,Ali S. Abdelhameed
出处
期刊:Profiles of Drug Substances, Excipients and Related Methodology
日期:2020-01-01
卷期号:: 1-39
被引量:4
标识
DOI:10.1016/bs.podrm.2019.10.001
摘要
Azilsartan is used for treatment of the high blood pressure (hypertension). Reducing high blood pressure enables avoid strokes, heart attacks and problems of kidneys. Azilsartan comes under the name angiotensin receptor blocker (ARBs) as a class of drugs. It acts by relaxing blood vessels to make it easier for blood to flow. Azilsartan Medoxomil's a comprehensive profile containing the description, formulae, Elemental Analysis, Uses and application. Furthermore, methods and schemes are outlined for the preparation of the drug substance. The physical properties of the medication include constant of ionization, solubility, X-ray powder diffraction pattern, differential scanning calorimetry, thermal conduct and spectroscopic studies are investigated. The methods employed in bulk medicines and/or in pharmaceutical formulations to analyze the drug substance include spectrophotometric, electrochemical and the chromatographic methods. Other studies on this drug substance include drug stability, Pharmaceutical Applications, Mechanism of Action, Pharmacodynamics, and a Dosing Information are reviewed. At the end of this profile, there are more than sixty references were listed.
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