Clinical Guidelines for Stroke Management (2010) developed by the National Stroke Foundation (NSF) has updated and amalgamated the two previously NHMRC approved guidelines developed by the NSF: Clinical Guidelines for Acute Stroke Management (2007) and Clinical Guidelines for Stroke Rehabilitation and Recovery (2005). This guideline reflects the need for acute and post acute services to provide seamless care to those affected by stroke and their families. This edition of the guideline importantly includes new information on fatigue, goal setting, secondary prevention measures for those on hormone replacement therapy or who are using oral contraception, oral hygiene, cognitive communication deficits, behavioural change and the amount and timing of rehabilitation. Many existing topics have been significantly revised including management of TIA, contracture, swelling of extremities and driving.