Clinical and Biochemical Differences in Patients with Pure Calcium Oxalate Monohydrate and Calcium Oxalate Dihydrate Kidney Stones

No AccessJournal of Urology1 Mar 1994Clinical and Biochemical Differences in Patients with Pure Calcium Oxalate Monohydrate and Calcium Oxalate Dihydrate Kidney Stones A.E. Pierratos, H. Khalaff, P.T. Cheng, K. Psihramis, and M.A.S. Jewett A.E. PierratosA.E. Pierratos , H. KhalaffH. Khalaff , P.T. ChengP.T. Cheng , K. PsihramisK. Psihramis , and M.A.S. JewettM.A.S. Jewett View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)35017-6AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail To examine the factors and patient characteristics predisposing to formation of calcium oxalate monohydrate or calcium oxalate dihydrate kidney stones, we compared blood and 24-hour urine tests, gender distribution and patient age in 2 groups of patients with pure calcium oxalate monohydrate (422) and calcium oxalate dihydrate (68) stones treated at the lithotripsy unit of the Wellesley Hospital and University of Toronto during 4 years. The calcium oxalate monohydrate group included relatively more women (31% versus 16% in the calcium oxalate dihydrate group, chi-square 7.89, p = 0.005). Patients were older in the calcium oxalate monohydrate group (59 ± 13 versus 51 ± 13 years, p = 0.001). The calcium oxalate monohydrate group had lower urinary calcium (4.19 ± 2.34 versus 7.19 ± 3.38mmol, per day, p <0.0001), calcium oxalate relative saturation rate (6.9 ± 3.9 versus 8.9 ± 3.3, p = 0.001), brushite relative saturation rate (0.7 ± 0.8 versus 1.2 ± 0.9, p = 0.0001) and urinary pH (5.72 ± 0.75 versus 5.93 ± 0.72). When corrected for patient age and gender, the calcium oxalate dihydrate group still had higher urine calcium levels. Higher urine pH in the calcium oxalate dihydrate group was age-related. In summary, we present evidence that calcium oxalate dihydrate stones are relatively more common among younger male patients with higher urine calcium levels and higher urine pH. © 1994 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByKrambeck A, Lieske J, Li X, Bergstralh E, Melton L and Rule A (2018) Effect of Age on the Clinical Presentation of Incident Symptomatic Urolithiasis in the General PopulationJournal of Urology, VOL. 189, NO. 1, (158-164), Online publication date: 1-Jan-2013.LEE Y, HUANG W, LU C, TSAI J and HUANG J (2018) Stone Recurrence Predictive Score (SRPS) for Patients with Calcium Oxalate StonesJournal of Urology, VOL. 170, NO. 2, (404-407), Online publication date: 1-Aug-2003.LEE Y, HUANG W, TSAI J and HUANG J (2018) THE EFFICACY OF POTASSIUM CITRATE BASED MEDICAL PROPHYLAXIS FOR PREVENTING UPPER URINARY TRACT CALCULI: A MIDTERM FOLLOWUP STUDYJournal of Urology, VOL. 161, NO. 5, (1453-1457), Online publication date: 1-May-1999.ASPLIN J, LINGEMAN J, KAHNOSKI R, MARDIS H, PARKS J and COE F (2018) METABOLIC URINARY CORRELATES OF CALCIUM OXALATE DIHYDRATE IN RENAL STONESJournal of Urology, VOL. 159, NO. 3, (664-668), Online publication date: 1-Mar-1998. Volume 151Issue 3March 1994Page: 571-574 Advertisement Copyright & Permissions© 1994 by The American Urological Association Education and Research, Inc.Keywordsurinary calculicalcium oxalate monohydratecalcium oxalate dihydrateMetricsAuthor Information A.E. Pierratos More articles by this author H. Khalaff More articles by this author P.T. Cheng More articles by this author K. Psihramis More articles by this author M.A.S. Jewett More articles by this author Expand All Advertisement PDF DownloadLoading ...