Lv3
206 积分 2023-04-10 加入
Alanyl-tRNA synthetase, AARS1, is a lactate sensor and lactyltransferase that lactylates p53 and contributes to tumorigenesis
2小时前
待确认
AARS1 and AARS2 sense l-lactate to regulate cGAS as global lysine lactyltransferases
2小时前
待确认
A chemical screen identifies PRMT5 as a therapeutic vulnerability for paclitaxel-resistant triple-negative breast cancer
1个月前
已完结
Ketogenic diet reshapes cancer metabolism through lysine β-hydroxybutyrylation
2个月前
已完结
Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma
3个月前
已完结
Phase separation of SPIN1 through its IDR facilitates histone methylation readout and tumorigenesis
3个月前
已完结
TRIM24 is critical for the cellular response to DNA double-strand breaks through regulating the recruitment of MRN complex
3个月前
已完结
Demethylzeylasteral targets lactate by inhibiting histone lactylation to suppress the tumorigenicity of liver cancer stem cells
3个月前
已完结
Profiling nuclear cysteine ligandability and effects on nuclear localization using proximity labeling-coupled chemoproteomics
3个月前
已完结
A glycolytic metabolite bypasses “two-hit” tumor suppression by BRCA2
3个月前
已完结
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