Lv51
1116 积分 2022-01-22 加入
Heteroaryl Glutarimides and Dihydrouracils as Cereblon Ligand Scaffolds for Molecular Glue Degrader Discovery
3小时前
已完结
Next steps for targeted protein degradation
3小时前
已完结
Discovery of Pyrazolo[1,5,4-de]quinoxalin-2(3H)-one Derivatives as Highly Potent and Selective PARP1 Inhibitors
5小时前
已完结
A molecular glue degrader of the WIZ transcription factor for fetal hemoglobin induction
3天前
已完结
Targeted Degradation of the Wiz Transcription Factor for Gamma Globin De-Repression
3天前
已关闭
Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models
3天前
已完结
Discovery and Optimization of First-in-Class Molecular Glue Degraders of the WIZ Transcription Factor for Fetal Hemoglobin Induction to Treat Sickle Cell Disease
3天前
已完结
A New Amino Acid for Improving Permeability and Solubility in Macrocyclic Peptides through Side Chain-to-Backbone Hydrogen Bonding
7天前
已完结
DNA damage response inhibitors in cancer therapy: lessons from the past, current status and future implications
8天前
已完结
Property-based optimisation of PROTACs
8天前
已完结
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