Lv71
3370 积分 2023-05-11 加入
Structure-based design and disulfide stapling of interfacial cyclic peptidic inhibitors from thymic stromal lymphopoietin (TSLP) receptor to competitively target TSLP
2天前
已完结
Pharmacological Chaperones for GCase that Switch Conformation with pH Enhance Enzyme Levels in Gaucher Animal Models
5天前
已完结
Pharmacological Chaperones for GCase that Switch Conformation with pH Enhance Enzyme Levels in Gaucher Animal Models
8天前
已完结
GraMDTA: Multimodal Graph Neural Networks for Predicting Drug-Target Associations
12天前
已完结
Discovery and characterization of novel TRPML1 agonists
13天前
已完结
Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of β-Glucocerebrosidase
15天前
已完结
TREM2 — a key player in microglial biology and Alzheimer disease
15天前
已完结
Discovery of a Small Molecule TREM2 Agonist with Improved In Vitro Pharmacokinetic Profile and Validated Target Engagement
15天前
已完结
Selective JAK1 inhibitors and the therapeutic applications thereof: a patent review (2016–2023)
15天前
已完结
Target sequence-conditioned design of peptide binders using masked language modeling
1个月前
已完结
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