Lv511
1506 积分 2024-07-19 加入
Targeting APRIL in the treatment of glomerular diseases
1天前
已完结
Synthetic Strategy and Evaluation of the Benzyloxy Benzylamide Derivatives as Thymic Stromal Lymphopoietin Modulators for the Treatment of Atopic Dermatitis
1天前
已完结
Discovery and Characterization of a Bicyclic Peptide (Bicycle) Binder to Thymic Stromal Lymphopoietin
2天前
已完结
Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator
6天前
已完结
Identification of a RANKL/TNF-α Dual-Inhibitor as a Potential Disease-Modifying Agent for the Treatment of Knee Osteoarthritis
8天前
已完结
Design, Synthesis, and Biological Evaluation of Heterocycle-Fused Celastrol Derivatives as Potent Antiosteoporosis Agents by Blocking RANKL-Induced Activation of the NF-κB and MAPK Signaling Pathways
8天前
已完结
Analyses of Recent Hit-Finding Campaigns for Difficult Targets Provides Guidance for Informed Integrated Hit Discovery
9天前
已完结
Structural and molecular characterization of a small-molecule TNF-α–TNFR1 inhibitor modulating cell death signaling
12天前
已完结
An orally active, small-molecule TNF inhibitor that disrupts the homotrimerization interface improves inflammatory arthritis in mice
12天前
已完结
Unravelling the potential of small molecule tumor necrosis factor-α (TNF) inhibitors: A comprehensive review
16天前
已完结