Lv41
590 积分 2023-01-16 加入
Discovery of a Novel Macrocyclic Noncovalent CDK7 Inhibitor for Cancer Therapy
5小时前
已完结
2023 FDA approvals
7个月前
已完结
Discovery of lirafugratinib (RLY-4008), a highly selective irreversible small-molecule inhibitor of FGFR2
7个月前
已完结
Crystallography-Guided Optimizations of the Keap1–Nrf2 Inhibitors on the Solvent Exposed Region: From Symmetric to Asymmetric Naphthalenesulfonamides
8个月前
已完结
Tumor-selective activity of RAS-GTP inhibition in pancreatic cancer
8个月前
已完结
A conformation-locking inhibitor of SLC15A4 with TASL proteostatic anti-inflammatory activity
1年前
已完结
Selective Wee1 Inhibitors Led to Antitumor Activity In Vitro and Correlated with Myelosuppression
1年前
已完结
Identification of Novel Small Molecule Ligands for JAK2 Pseudokinase Domain
1年前
已完结
Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation
1年前
已完结
Insight from Linker Investigations: Discovery of a Novel Phenylbenzothiazole Necroptosis Inhibitor Targeting Receptor-Interacting Protein Kinase 1 (RIPK1) from a Phenoxybenzothiazole Compound with Dual RIPK1/3 Targeting Activity
1年前
已完结
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