Lv4
570 积分 2023-01-16 加入
Structure-Based Design of Novel Alkynyl Thio-Benzoxazepinone Receptor-Interacting Protein Kinase-1 Inhibitors: Extending the Chemical Space from the Allosteric to ATP Binding Pockets
8天前
已完结
From Hit to Lead: Structure-Based Optimization of Novel Selective Inhibitors of Receptor-Interacting Protein Kinase 1 (RIPK1) for the Treatment of Inflammatory Diseases
8天前
已完结
RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer
8天前
已完结
Tozasertib Analogues as Inhibitors of Necroptotic Cell Death
9天前
已完结
Architecture and activation of single-pass transmembrane receptor guanylyl cyclase
29天前
已完结
Covalent Inhibitors of KEAP1 with Exquisite Selectivity
1个月前
已完结
The Missing Link(er): A Roadmap to Macrocyclization in Drug Discovery
1个月前
已完结
Discovery of a Novel Macrocyclic Noncovalent CDK7 Inhibitor for Cancer Therapy
1个月前
已完结
Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3Kα Mutant Protein
2个月前
已完结
Discovery of a Novel Macrocyclic Noncovalent CDK7 Inhibitor for Cancer Therapy
3个月前
已完结
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