Lv1
72 积分 2024-08-02 加入
Alanyl-tRNA synthetase, AARS1, is a lactate sensor and lactyltransferase that lactylates p53 and contributes to tumorigenesis
4小时前
已完结
Oncometabolite lactate enhances breast cancer progression by orchestrating histone lactylation-dependent c-Myc expression
6天前
已完结
Glucose-driven histone lactylation promotes the immunosuppressive activity of monocyte-derived macrophages in glioblastoma
10天前
已完结
H3K9 lactylation in malignant cells facilitates CD8+ T cell dysfunction and poor immunotherapy response
17天前
已完结
Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments
18天前
已完结
Lactate modulates RNA splicing to promote CTLA-4 expression in tumor-infiltrating regulatory T cells
19天前
已完结
H3K18 Lactylation Potentiates Immune Escape of Non-Small Cell Lung Cancer
23天前
已完结
IRE1α silences dsRNA to prevent taxane-induced pyroptosis in triple-negative breast cancer
23天前
已完结
Hepatic stellate cells promote hepatocellular carcinoma development by regulating histone lactylation: Novel insights from single-cell RNA sequencing and spatial transcriptomics analyses
29天前
已完结
Histone lactylation drives CD8+ T cell metabolism and function
1个月前
已完结
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