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60 积分 2021-03-16 加入
Design, Synthesis, and Pharmacological Characterization of N-(4-(2 (6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)yl)ethyl)phenyl)quinazolin-4-amine Derivatives: Novel Inhibitors Reversing P-Glycoprotein-Mediated Multidrug Resistance
22小时前
已完结
Membrane‐Bounded Intracellular E3 Ubiquitin Ligase‐Targeting Chimeras (MembTACs) for Targeted Membrane Protein Degradation
5天前
已完结
Discovery of a Silicon-Containing Pan-Genotype Hepatitis C Virus NS5A Inhibitor
15天前
已完结
Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia
18天前
已完结
The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy
18天前
已完结
The New Frontier: Merging Molecular Glue Degrader and Antibody–Drug Conjugate Modalities To Overcome Strategic Challenges
1个月前
已完结
Iron-catalyzed arene C−H hydroxylation
1个月前
已完结
Discovery of orally bioavailable ALK PROTACs based Ceritinib against ALK positive cancers
3个月前
已完结
Discovery of a Highly Potent, N-terminal Domain-targeting degrader of AR-FL/AR-V7 for the treatment of Prostate Cancer
3个月前
已完结
Synthesis and Biological Evaluation of B-Cell Lymphoma 6 Inhibitors of N-Phenyl-4-pyrimidinamine Derivatives Bearing Potent Activities against Tumor Growth
3个月前
已完结
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