Lv4
710 积分 2022-04-17 加入
Design, synthesis, and biological evaluation of novel (1-thioxo-1,2,3,4-tetrahydro-β-carbolin-9-yl)acetic acids as selective inhibitors for AKR1B1
6天前
已完结
Discovery of BW710 as a Potent, Selective and Orally Bioavailable Fibroblast Growth Factor Receptor 2 (FGFR2) Inhibitor
13天前
已完结
Phase 2 Trial of Baxdrostat for Treatment-Resistant Hypertension
14天前
已完结
Selective and Potent Molecular Glue Degraders for NIMA‐related Kinase 7
26天前
已完结
NEK7: a new target for the treatment of multiple tumors and chronic inflammatory diseases
26天前
已完结
In silico study to identify novel NEK7 inhibitors from natural source by a combination strategy
27天前
已完结
Discovery of Novel Biaryl Urea Derivatives against IL-1β Release with Low Toxicity Based on NEK7 Inhibitor
27天前
已完结
Discovery and Development of NLRP3 Inhibitors Targeting the LRR Domain to Disrupt NLRP3-NEK7 Interaction for the Treatment of Rheumatoid Arthritis
27天前
已完结
NEK7 phosphorylation amplifies NLRP3 inflammasome activation downstream of potassium efflux and gasdermin D
27天前
已完结
Turning Off STAT6 with a Targeted Degrader
1个月前
已完结
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