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2023-06-16 加入
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. Discovery of highly potent human glutaminyl cyclase (QC) inhibitors as anti-Alzheimer’s agents by the combination of pharmacophore-based and structure-based design
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4D-QSAR, ADMET properties, and molecular dynamics simulations for designing N-substituted urea/thioureas as human glutaminyl cyclase inhibitors
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Synthesis and Evaluation of a Novel PET Radioligand for Imaging Glutaminyl Cyclase Activity as a Biomarker for Detecting Alzheimer’s Disease
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Glutaminyl cyclases, the potential targets of cancer and neurodegenerative diseases
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Discovery of potential scaffolds for glutaminyl cyclase inhibitors: Virtual screening, synthesis, and evaluation
5个月前
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Molecular mechanisms in Alzheimer's disease and related potential treatments such as structural target convergence of antibodies and simple organic molecules
8个月前
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用于肿瘤靶向谷氨酰胺限制的氧化还原响应前药
8个月前
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Small-Molecule Hydrophobic Tagging: A Promising Strategy of Druglike Technology for Targeted Protein Degradation
8个月前
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