Lv42
510 积分 2024-10-22 加入
Potent and Preferential Degradation of CDK6 via Proteolysis Targeting Chimera Degraders
1天前
已完结
EFS24 Failure, BRD4 Expression, and TP53 Are Linked to Reduced CDKN1A Expression in DLBCL and May be Targeted By Single-Agent Protac ARV-825 or in Synergistic Combination with the CDK4/6 Inhibitor Abemaciclib
3天前
求助中
EFS24 Failure, BRD4 Expression, and TP53 Are Linked to Reduced CDKN1A Expression in DLBCL and May be Targeted By Single-Agent Protac ARV-825 or in Synergistic Combination with the CDK4/6 Inhibitor Abemaciclib
3天前
已关闭
EFS24 Failure, BRD4 Expression, and TP53 Are Linked to Reduced CDKN1A Expression in DLBCL and May be Targeted By Single-Agent Protac ARV-825 or in Synergistic Combination with the CDK4/6 Inhibitor Abemaciclib
3天前
已关闭
Discovery of the GSH responsive “Y-PROTACs” targeting ALK and CDK4/6 as a potential treatment for cancer
3天前
已完结
Syntheses of partially hydrogenated [1,2,4]triazolo[4,5-a]pyrimidine-4-ones through cyclisation of 2-arylidenehydrazino-6-methyl-4-pyrimidones
6天前
已完结
Single crystal XRD, spectroscopic, DFT studies and synthesis of [1,2,4]triazolo[4,3-a]pyrimidines
21天前
已完结
Discovery and preclinical evaluations of TQB3616, a novel CDK4-biased inhibitor
22天前
已完结
Synthesis and biological evaluation of 6-(pyrimidin-4-yl)-1H-pyrazolo[4,3-b]pyridine derivatives as novel dual FLT3/CDK4 inhibitors
22天前
已完结
Selective CDK4/6 inhibition of novel 1,2,3-triazole tethered acridinedione derivatives induces G1/S cell cycle transition arrest via Rb phosphorylation blockade in breast cancer models
22天前
已完结
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