Lv51
1130 积分 2022-08-29 加入
Discovery of 2-[1-(4-Chlorophenyl)cyclopropyl]-3-hydroxy-8-(trifluoromethyl)quinoline-4-carboxylic Acid (PSI-421), a P-Selectin Inhibitor with Improved Pharmacokinetic Properties and Oral Efficacy in Models of Vascular Injury
1年前
已完结
The Comparison of Machine Learning and Mechanistic In Vitro–In Vivo Extrapolation Models for the Prediction of Human Intrinsic Clearance
1年前
已完结
In Vitro-In Vivo Extrapolation and Scaling Factors for Clearance of Human and Preclinical Species with Liver Microsomes and Hepatocytes
1年前
已完结
The Role of Alcohol Dehydrogenase in Drug Metabolism: Beyond Ethanol Oxidation
1年前
已完结
Quantitative Translation of Substrate Intrinsic Clearance from Recombinant CYP1A1 to Humans
1年前
已完结
Recent advances in measurement of metabolic clearance, metabolite profile and reaction phenotyping of low clearance compounds
1年前
已完结
Addressing the Accuracy of Plasma Protein Binding Measurement for Highly Bound Compounds Using the Dilution Method
1年前
已完结
Special issue on applications of in vitro, in vivo, and modeling and simulation tools for central nervous system drug disposition
1年前
已完结
Early Drug-Induced Liver Injury Risk Screening: “Free,” as Good as It Gets
1年前
已完结
Consideration of the Unbound Drug Concentration in Enzyme Kinetics
1年前
已完结
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