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Design, synthesis and evaluation of EZH2-based PROTACs targeting PRC2 complex in lymphoma
14小时前
已完结
Design and Synthesis of EZH2-Based PROTACs to Degrade the PRC2 Complex for Targeting the Noncatalytic Activity of EZH2
15小时前
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Bridged Proteolysis Targeting Chimera (PROTAC) Enables Degradation of Undruggable Targets
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Discovery of a First-in-Class Degrader for the Lipid Kinase PIKfyve
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A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization
4天前
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Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation
8天前
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Identification of a novel Azaspirooxindolinone-based PROTAC for selective BTK degradation and enhanced anticancer activity
10天前
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Synthesis and Insecticidal Evaluation of Propesticides of Benzoylphenylureas
10天前
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Hydrophobic tag tethering degrader as a promising paradigm of protein degradation: Past, present and future perspectives
12天前
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Application and challenges of nitrogen heterocycles in PROTAC linker
12天前
已完结
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