Lv76
3210 积分 2022-07-29 加入
Discovery of a Novel Macrocyclic Noncovalent CDK7 Inhibitor for Cancer Therapy
5天前
已完结
Design, Synthesis, and Biological Evaluation of Novel Diaminopyrimidine Macrocycles as Fourth Generation Reversible EGFR Inhibitors That Overcome Clinical Resistance to Osimertinib Mediated by C797S Mutation
7天前
已完结
MET alterations in advanced non-small cell lung cancer
9天前
已完结
Clinical PARP inhibitors allosterically induce PARP2 retention on DNA
17天前
已完结
Synthesis and in vitro biological evaluation of 3-ethyl-1,5-naphthyridin-2(1H)-one derivatives as potent PARP-1 selective inhibitors and PARP-1 DNA trappers
17天前
已完结
Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD5305): A PARP1–DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPs
17天前
已完结
Targeting cancer with small molecule pan-KRAS degraders
23天前
已完结
A non-covalent inhibitor with pan-KRAS potential
23天前
已完结
Discovery and Optimization of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations
24天前
已完结
Overview of Current Type I/II Kinase Inhibitors
1个月前
已完结
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