Lv1
90 积分 2023-12-18 加入
Design and synthesis of the first indole-based blockers of Panx-1 channel
6天前
已完结
Design and discovery of C2-fluoroalkyl iminothiazine dioxides as BACE inhibitors
20天前
已完结
Discovery of Umibecestat (CNP520): A Potent, Selective, and Efficacious β-Secretase (BACE1) Inhibitor for the Prevention of Alzheimer’s Disease
20天前
已完结
Discovery and In Vivo Evaluation of ACT-660602: A Potent and Selective Antagonist of the Chemokine Receptor CXCR3 for Autoimmune Diseases
20天前
已完结
Design and discovery of C2-fluoroalkyl iminothiazine dioxides as BACE inhibitors
20天前
已完结
Discovery of 6-[(3S,4S)-4-Amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-3-(2,3-dichlorophenyl)-2-methyl-3,4-dihydropyrimidin-4-one (IACS-15414), a Potent and Orally Bioavailable SHP2 Inhibitor
21天前
已完结
Discovery of (R)-(3-fluoropyrrolidin-1-yl)(6-((5-(trifluoromethyl)pyridin-2-yl)oxy)quinolin-2-yl)methanone (ABBV-318) and analogs as small molecule Nav1.7/ Nav1.8 blockers for the treatment of pain
22天前
已完结
Application and assessment of deep learning for the generation of potential NMDA receptor antagonists
22天前
已完结
The Quantitative Structure-Activity Relationships between GABAA Receptor and Ligands based on Binding Interface Characteristic
23天前
已完结
AI in small-molecule drug discovery: a coming wave?
24天前
已完结
皖公网安备34019202002308
