Lv3
350 积分 2024-02-02 加入
Discovery of a Small Molecule TREM2 Agonist with Improved In Vitro Pharmacokinetic Profile and Validated Target Engagement
8天前
已完结
Structure‐Based Virtual Screening Identifies TREM2‐Targeted Small Molecules that Enhance Microglial Phagocytosis
8天前
已完结
High-throughput fragment screening identifies a new small molecule scaffold that modulates TREM2 Signaling
10天前
已关闭
The TREM2 agonistic antibody AL002 in early Alzheimer’s disease: a phase 2 randomized trial
24天前
已完结
Effects of a novel GABA‐B positive allosteric modulator, ASP8062, on alcohol cue‐elicited craving and naturalistic alcohol consumption in a multisite randomized, double‐blind, placebo‐controlled trial
27天前
已完结
Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKKε and Reveal Mechanisms for Selective Inhibition
28天前
已完结
Repression of RIPK1 kinase by INPP5D inhibits expression of diverse proinflammatory mediators and late-onset Alzheimer’s disease risk factors
1个月前
已完结
Cell surface display of a protein based on a tail-anchored membrane protein
2个月前
已完结
A Review of Amylin Peptide Receptor Activators for Obesity Pharmacotherapy
3个月前
已完结
Tyrphostin AG538 inhibits platelet activation and thrombosis via TREM2 agonism
3个月前
已完结
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