Lv11
20 积分 2024-07-07 加入
Quinazoline derivatives inhibit cell growth of prostate cancer as a WRN helicase dependent manner by regulating DNA damage repair and microsatellite instability
3小时前
已完结
Design, Synthesis, and Structure−Activity Relationship Studies of Triazolo-pyrimidine Derivatives as WRN Inhibitors for the Treatment of MSI Tumors
3小时前
已完结
Recent applications of click chemistry in drug discovery
1个月前
已完结
Structure- and Similarity-Based Survey of Allosteric Kinase Inhibitors, Activators, and Closely Related Compounds
1个月前
已完结
Design, synthesis and antitumor activity of 2-substituted quinazoline-4-amine derivatives
1个月前
已完结
The WRN helicase: resolving a new target in microsatellite unstable cancers
1个月前
已完结
Using a Function-First “Scout Fragment”-Based Approach to Develop Allosteric Covalent Inhibitors of Conformationally Dynamic Helicase Mechanoenzymes
1个月前
已完结
The Redox Protein High-Mobility Group Box 1 in Cell Death and Cancer
2个月前
已完结
Discovery of thiophen-2-ylmethylene bis-dimedone derivatives as novel WRN inhibitors for treating cancers with microsatellite instability
2个月前
已完结
Discovering potential WRN inhibitors from natural product database through computational methods
2个月前
已完结
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