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10 积分 2025-02-20 加入
Discovery and Synthesis of Heterobifunctional Degraders of Rearranged during Transfection (RET) Kinase
1天前
已完结
Discovery of an Efficacious RET PROTAC Degrader with Enhanced Antiproliferative Activity against Resistant Cancer Cells Harboring RET Solvent-Front Mutations
1天前
已完结
Design, synthesis and evaluation of (E)-1-(4-(2-(1H-pyrazol-5-yl)vinyl)phenyl) derivatives as next generation selective RET inhibitors overcoming RET solvent front mutations (G810C/R)
1天前
已完结
Discovery of a Selective and Orally Bioavailable RET Degrader with Effectiveness in Various Mutations
1天前
已完结
Discovery of 7-(1-methyl-1H-pyrazol-4-yl)-1,6-naphthyridine Derivatives as Potent Inhibitors of Rearranged During Transfection (RET) and RET Solvent-Front Mutants for Overcoming Selpercatinib Resistance
1天前
已完结
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