Lv1
20 积分 2024-09-24 加入
Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN
3天前
已完结
Mining the CRBN Target Space Redefines Rules for Molecular Glue-induced Neosubstrate Recognition
3天前
已完结
Mechanisms of Dupilumab
10天前
已完结
Heteroaryl Glutarimides and Dihydrouracils as Cereblon Ligand Scaffolds for Molecular Glue Degrader Discovery
10天前
已完结
Discovery of SD-436: A Potent, Highly Selective and Efficacious STAT3 PROTAC Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression
16天前
已完结
Humanized cereblon mice revealed two distinct therapeutic pathways of immunomodulatory drugs
22天前
已完结
Targeted Degradation of the Wiz Transcription Factor for Gamma Globin De-Repression
22天前
已关闭
Targeted Degradation of the Wiz Transcription Factor for Gamma Globin De-Repression
22天前
已关闭
CC-90009: A Cereblon E3 Ligase Modulating Drug That Promotes Selective Degradation of GSPT1 for the Treatment of Acute Myeloid Leukemia
22天前
已完结
Uncovering PROTAC Sensitivity and Efficacy by Multidimensional Proteome Profiling: A Case for STAT3
1个月前
已完结
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