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30 积分 2020-12-06 加入
A Chiral Pool Strategy for the Synthesis of a SMARCA2 Degrading PROTAC
2天前
已完结
Process Development for the Synthesis of BI 1702135: A Concise Design Enabled by Selective Acylation of a 2-Aminobenzimidazole Intermediate
2天前
已完结
Discovery of a Novel CRBN-Recruiting cGAS PROTAC Degrader for the Treatment of Ulcerative Colitis
12天前
已完结
STAT6 phosphorylation inhibitors block eotaxin-3 secretion in bronchial epithelial cells
1个月前
已完结
Design and Discovery of Preclinical Candidate LYG-409 as a Highly Potent and Selective GSPT1 Molecular Glue Degraders
1个月前
已完结
Discovery of High-Affinity SMARCA2/4 Bromodomain Ligands and Development of Potent and Exceptionally Selective SMARCA2 PROTAC Degraders
1个月前
已完结
A selective small-molecule STAT5 PROTAC degrader capable of achieving tumor regression in vivo
1个月前
已完结
Discovery of a Highly Potent and Orally Bioavailable STAT3 Dual Phosphorylation Inhibitor for Pancreatic Cancer Treatment
1个月前
已完结
Discovery of AK-1690: A Potent and Highly Selective STAT6 PROTAC Degrader
2个月前
已完结
Evaluation of Cereblon-Directing Warheads for the Development of Orally Bioavailable PROTACs
2个月前
已完结
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