cis2014
Lv65
2250 积分
2022-08-25 加入
-
Design, Synthesis, and Biological Evaluation of 1,2,4-Oxadiazole Derivatives Containing an Aryl Carboxylic Acid Moiety as Potent Sarbecovirus Papain-like Protease Inhibitors
16小时前
已完结
-
Tertiary Amines as Temporary Masked Secondary Amines: A Direct Access to 5-Dialkylamino-1,2,4-oxadiazoles from 1,2,4-Oxadiazol-5(4H)-ones
1天前
已完结
-
Application and challenges of nitrogen heterocycles in PROTAC linker
29天前
已完结
-
Molecular Glue Discovery: Current and Future Approaches
30天前
已完结
-
Discovery of CW-3308 as a Potent, Selective, and Orally Efficacious PROTAC Degrader of BRD9
1个月前
已完结
-
Discovery of DS-9300: A Highly Potent, Selective, and Once-Daily Oral EP300/CBP Histone Acetyltransferase Inhibitor
1个月前
已完结
-
Design, synthesis and biological evaluation of (R)-5-methylpyrrolidin-2-ones as p300 bromodomain inhibitors with Anti-Tumor activities in multiple tumor lines
1个月前
已完结
-
Orally Bioavailable CBP and p300 Selective Degraders for the Treatment of AR- and ER-dependent Cancers
1个月前
已完结
-
Discovery and Characterization of Active CBP/EP300 Degraders Targeting the HAT Domain
1个月前
已完结
-
Exploration of bromodomain ligand-linker conjugation sites for efficient CBP/p300 heterobifunctional degrader activity
1个月前
已完结