Lv4
480 积分 2021-07-13 加入
Repression of RIPK1 kinase by INPP5D inhibits expression of diverse proinflammatory mediators and late-onset Alzheimer’s disease risk factors
17天前
已完结
The Discovery of 7-Isopropoxy-2-(1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl)-N-(6-methylpyrazolo[1,5-a]pyrimidin-3-yl)imidazo[1,2-a]pyrimidine-6-carboxamide (BIO-7488), a Potent, Selective, and CNS-Penetrant IRAK4 Inhibitor for the Treatment of Ischemic Stroke
19天前
已完结
Human organoids as 3D in vitro platforms for drug discovery: opportunities and challenges
1个月前
已完结
The Alzheimer’s disease risk genes MS4A4A and MS4A6A cooperate to negatively regulate TREM2 and microglia states
1个月前
已完结
Immune dysfunction in Alzheimer disease
1个月前
已完结
Targeting Neutrophil-Mediated Inflammation: Identification of Pyrazolidinone Carboxamide Derivatives as Potent Selective Inhibitors of Formyl Peptide Receptor 1 (FPR1)-Activated Neutrophils
1个月前
已完结
GPCR drug discovery: new agents, targets and indications
1个月前
已完结
Targeting Neutrophil-Mediated Inflammation: Identification of Pyrazolidinone Carboxamide Derivatives as Potent Selective Inhibitors of Formyl Peptide Receptor 1 (FPR1)-Activated Neutrophils
1个月前
已完结
From geroscience to precision geromedicine: Understanding and managing aging
1个月前
已完结
Targeting formyl peptide receptor 1 reduces brain inflammation and neurodegeneration
1个月前
已完结
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