Lv31
330 积分 2024-08-16 加入
Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors
4小时前
求助中
Discovery of c-Kit as a New Therapeutic Target in LPS-Induced Acute Lung Injury through Novel Phenylamide Derivative D9
7天前
已完结
Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted Cancers
1个月前
已完结
Fragment-to-Lead Medicinal Chemistry Publications in 2023
1个月前
已完结
A Medicinal Chemistry Perspective on FDA-Approved Small Molecule Drugs with a Covalent Mechanism of Action
1个月前
已完结
Design and Discovery of Preclinical Candidate LYG-409 as a Highly Potent and Selective GSPT1 Molecular Glue Degraders
2个月前
已完结
Evaluation of Cereblon-Directing Warheads for the Development of Orally Bioavailable PROTACs
2个月前
已完结
Structure–Activity Relationship Studies of an Autophagy Inhibitor That Targets the ATG14L-Beclin1 Protein–Protein Interaction Reveal Modifications That Improve Potency and Solubility and Maintain Selectivity
2个月前
已完结
Development of Substituted Phenyl Dihydrouracil as the Novel Achiral Cereblon Ligands for Targeted Protein Degradation
2个月前
已完结
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