Lv3
340 积分 2024-08-16 加入
Lysine-Targeted Covalent Inhibitors of PI3Kδ Synthesis and Screening by In Situ Interaction Upgradation
2天前
已完结
Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors
11天前
已完结
Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson’s Disease
11天前
已完结
The Discovery of MORF-627, a Highly Selective Conformationally-Biased Zwitterionic Integrin αvβ6 Inhibitor for Fibrosis
16天前
已完结
The Missing Link(er): A Roadmap to Macrocyclization in Drug Discovery
1个月前
已完结
Discovery and Optimization of N-Heteroaryl Indazole LRRK2 Inhibitors
1个月前
已完结
Targeting Bromodomain-Selective Inhibitors of BET Proteins in Drug Discovery and Development
2个月前
已完结
Discovery of TRPA1 Antagonist GDC-6599: Derisking Preclinical Toxicity and Aldehyde Oxidase Metabolism with a Potential First-in-Class Therapy for Respiratory Disease
2个月前
已完结
Discovery of GNE-6893, a Potent, Selective, Orally Bioavailable Small Molecule Inhibitor of HPK1
2个月前
已完结
The Discovery of Exarafenib (KIN-2787): Overcoming the Challenges of Pan-RAF Kinase Inhibition
2个月前
已完结
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