Lv6
1770 积分 2023-07-12 加入
Elimination of tucatinib, a small molecule kinase inhibitor of HER2, is primarily governed by CYP2C8 enantioselective oxidation of gem-dimethyl
1天前
已完结
Pharmacokinetics and Safety of Momelotinib in Subjects With Hepatic or Renal Impairment
4天前
已完结
A Randomized, Open‐Label, Two‐Sequence, Crossover Trial Evaluating the Bioequivalence, and Pharmacokinetics of Two Sulfamethoxazole/Trimethoprim Tablet Formulations in Healthy Chinese Volunteers Under Fasting Conditions
20天前
已完结
Investigation of ponatinib metabolism and drug-drug interactions with lycopene and shikonin in vitro and in vivo
22天前
已完结
PBPK modeling of the antidepressant doxepin incorporating CYP2D6 genotype for precision pharmacotherapy
28天前
已完结
Drug-induced liver injury: Pathogenesis, epidemiology, clinical features, and practical management
29天前
已完结
Identification and Functional Assessment of Eight CYP3A4 Allelic Variants *39–*46 Detected in the Chinese Han Population
29天前
已完结
The effect of apatinib on pharmacokinetic profile of buspirone both in vivo and in vitro
29天前
已关闭
Inhibition Mechanism of Ketamine‐Apatinib by CYP2C9 and 3A4: A Prediction of Possible Drug‐Drug Interaction
29天前
已完结
CYP genetic polymorphism, and CYP3A inducers and inhibitors regulate apatinib metabolism: Consequences for drug exposure and toxicity risks
29天前
已完结