Lv1
60 积分 2024-04-24 加入
Disproportionation of a crystalline citrate salt of a developmental pharmaceutical compound: Characterization of the kinetics using pH monitoring and online Raman spectroscopy plus quantitation of the crystalline free base form in binary physical mixtures using FT-Raman, XRPD and DSC
2天前
已完结
Rational Design and Optimization of a Potent IDO1 Proteolysis Targeting Chimera (PROTAC)
1个月前
已完结
Novel TOPK Inhibitor HI-TOPK-032 Effectively Suppresses Colon Cancer Growth
5个月前
已完结
Architecture of the MKK6-p38α complex defines the basis of MAPK specificity and activation
5个月前
已完结
GCM2突变相关原发性甲状旁腺功能亢进症的发病机制及临床特点
8个月前
已完结
Discovery of Clinical Candidate GLPG3970: A Potent and Selective Dual SIK2/SIK3 Inhibitor for the Treatment of Autoimmune and Inflammatory Diseases
9个月前
已完结
Discovery of GLPG2737, a Potent Type 2 Corrector of CFTR for the Treatment of Cystic Fibrosis in Combination with a Potentiator and a Type 1 Co-corrector
10个月前
已完结
Synthesis and Structure–Activity Relationships of 2,5-Dimethoxy-4-Substituted Phenethylamines and the Discovery of CYB210010: A Potent, Orally Bioavailable and Long-Acting Serotonin 5-HT2 Receptor Agonist
10个月前
已完结
Discovery of TP0628103: A Highly Potent and Selective MMP-7 Inhibitor with Reduced OATP-Mediated Clearance Designed by Shifting Isoelectric Points
11个月前
已完结
Discovery of Darovasertib (NVP-LXS196), a Pan-PKC Inhibitor for the Treatment of Metastatic Uveal Melanoma
11个月前
已完结
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