Lv31
244 积分 2021-10-25 加入
The mitochondrial enzyme pyruvate carboxylase restricts pancreatic β-cell senescence by blocking p53 activation
4天前
已完结
Discovery of MD-265: A Potent MDM2 Degrader That Achieves Complete Tumor Regression and Improves Long-Term Survival of Mice with Leukemia
5天前
已完结
Estrogen receptor α aggravates intestinal inflammation via promoting the activation of NLRP3 inflammasome
6天前
已完结
Discovery of ERD-3111 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader with Strong Antitumor Activity
14天前
已完结
Discovery of ERD-1233 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader for the Treatment of ER+ Human Breast Cancer
14天前
已完结
Discovery of ERD-1233 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader for the Treatment of ER+ Human Breast Cancer
17天前
已完结
A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos
18天前
已完结
Overcoming IMiD resistance in T-cell lymphomas through potent degradation of ZFP91 and IKZF1
18天前
已关闭
Fluorescence theranostic PROTACs for real-time visualization of ERα degradation
23天前
已完结
Discovery of Novel ERα and Aromatase Dual-Targeting PROTAC Degraders to Overcome Endocrine-Resistant Breast Cancer
23天前
已完结
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