Lv312
204 积分 2025-01-15 加入
A High-Throughput Screening Pipeline to Identify Methyltransferase and Exonuclease Inhibitors of SARS-CoV-2 NSP14
3天前
已完结
Discovery of FHD-286, a First-in-Class, Orally Bioavailable, Allosteric Dual Inhibitor of the Brahma Homologue (BRM) and Brahma-Related Gene 1 (BRG1) ATPase Activity for the Treatment of SWItch/Sucrose Non-Fermentable (SWI/SNF) Dependent Cancers
4天前
已完结
The expanding repertoire of covalent warheads for drug discovery
16天前
已完结
Exploring PRMT5 Inhibition As a Therapeutic Strategy in Primary and Secondary Hemophagocytic Lymphohistiocytosis
19天前
已完结
Exploration of Degrons and Their Ability to Mediate Targeted Protein Degradation
23天前
已完结
Discovery of a Highly Potent and Selective Degrader Targeting Hematopoietic Prostaglandin D Synthase via In Silico Design
23天前
已完结
A Mathematical Model for Covalent Proteolysis Targeting Chimeras: Thermodynamics and Kinetics underlying Catalytic Efficiency
23天前
已完结
Discovery of CW-3308 as a Potent, Selective, and Orally Efficacious PROTAC Degrader of BRD9
23天前
已完结
A CRISPR activation screen identifies FBXO22 supporting targeted protein degradation
24天前
已完结
Recruitment of FBXO22 for Targeted Degradation of NSD2
24天前
已完结
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