Lv1
30 积分 2023-04-08 加入
Celastrol induces ferroptosis in activated HSCs to ameliorate hepatic fibrosis via targeting peroxiredoxins and HO-1
1天前
已完结
Modulation of taxane binding to tubulin curved and straight conformations by systematic 3′N modification provides for improved microtubule binding, persistent cytotoxicity and in vivo potency
2天前
已完结
Irreversible kinase inhibitors targeting to cysteine residues and their applications in cancer therapy
3天前
已完结
Cysteine-targeted Irreversible Inhibitors of Tyrosine Kinases and Key Interactions
4天前
已完结
Design, synthesis, and evaluation of antitumor activity of novel C-6 sulfhydryl-substituted and 20-substituted derivatives of celastrol
1个月前
已完结
Scaffold hopping of celastrol provides derivatives containing pepper ring, pyrazine and oxazole substructures as potent autophagy inducers against breast cancer cell line MCF-7
1个月前
已完结
Synthesis and biological evaluation of celastrol derivatives as potential anti-glioma agents by activating RIP1/RIP3/MLKL pathway to induce necroptosis
1个月前
已完结
Celastrol suppresses colorectal cancer via covalent targeting peroxiredoxin 1
1个月前
已完结
Synthesis of a celastrol derivative as a cancer stem cell inhibitor through regulation of the STAT3 pathway for treatment of ovarian cancer
1个月前
已完结
Synthesis and anticancer properties of celastrol derivatives involved in the inhibition of VEGF
1个月前
已完结
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